Kafka,The Metamorphosis Essay Example for Free

Kafka,The Metamorphosis Essay As Gregor saw his many legs waving in the air it symbolizes the rejection of different people because as a traveling salesman he used to move constantly from one place to another and in the habit of waking up in unfamiliar surroundings and various circumstances. He must show his patience, perseverance and eagerness to induce many customers because from that he can earn his living. But as we all know not all the people that we used to mingle with can accept and entertain us positively. The weight on Gregor’s life represents the resistance to change in family tradition that he is the financial head of the household; nobody else probably works in his family; their whole present and comfortable existence relies upon Gregor’s employment. Most of his burden is the debt which his father owes to the employer for whom Gregor now works. His mere condition shows the exploitation of one by many because the reactions of his own family revealed that he is just an impending burden to them. They care for him but they are so horrified by his presence that’s why they take to shutting Gregor into his room. They tend to shrink back whenever he reveals himself and his father embedded one of the apples in his back, causing an infection. As he hides himself underneath a sheet is the metaphor for rejection of sick people because it attests that he is afraid to see and to be seen by other people because of that his family becomes the jailer, they locked Gregor in from the outside. Though bereft of human contact, he is still concern for his family and at the same time mad at them for neglecting him. We can de – humanize our enemies by letting them realize their fault and shortcomings; in short we try to touch their conscience. Just like the way Gregor did in this story, he would have left his family out of love and taken their burden away. He returns to his room and collapses, finally giving in to his wound and starvation. I think he did that for one good reason to open the mind of his family that during the days of helping them and even sacrificing for their benefits, he didn’t even murmured or ask something in return coming from them. The Nazi treatment of Jews in the hand of Germany headed by Hitler was violent and so bloody. Hitler called the Jews as his enemies. Enemy defined as opponent or hostile nation. When we called somebody as an opponent it simply meant that we must do something that would hurt them, made them miserable and finally killed them. These are the objectives of Hitler to all his enemies. He pursued boycotts for the Jewish shops and businesses in ! 933; in 1934, the law banned all the Jewish form public places; plundered the Jewish teachers, civil servants and lawyers. Some of the maltreatments were removing the privilege to the Jews to become a German citizen; restriction of inter racial marriage;working and holding property in Germany; the assassination of many Jews and yet penalizing them. The reason why all of these things happened because of selfish desire and greediness. These are not good if many would suffer and be affected by covetousness and hatred. Hostility toward or discrimination against Jews as a religious, ethnic, or racial group is considered as the meaning of anti – semitism. The anti – Semitism in Europe was almost the same predicament of that in the Nazi, Germany. The hatred to the Jews that’s inside their heart becomes deeper and deeper. One example of this was a soccer match between the Israeli and Belgian national teams in Hasselt, Belgium, when Muslim fans waved Hamas and Hezbollah banners, and chanted: Jews to the gas chambers! and Strangle the Jews! (taken from the Cancer of Anti – Semitism in Europe). We can conclude in this simple illustration that the hatred developed in the past still lingers in the present situation. The suppression of one’s freedom and stepping onto the human rights of a person developed them in two personalities: they may become weak and dependent while on the other hand a person may possess a strong will to fight and defend himself from his enemies. According to Iris Bruce and Cassill, many interpretations of Franz Kafkas writings have accentuated their psychological, religious, existential and moral dimensions and initiated a whole genre of the kqfkaesque which summon up associations of the grotesque and absurd but is rarely associated with a sense of humour. A Kafkaesque, or Kafka-like situation being one of a strange or nightmarish quality become a part of the language from Kafka’s name. Generally, after World War II (and fundamentally due to the prominence of New Criticism and Existentialism in the literary academies during this time), a Kafka myth has crystallized which stresses Kafkas existential anguish: interpretations, be they religious, phenomenological, existentialist, symbolic or allegorical, center on the psychology of the author, who is presented as being overcome by the sense of absurdity and alienation so prevalent in twentieth. Where this metaphysical approach in literary translation as a discipline has been most detrimental is in its emphasis on the universal rather than on specific textual elements, in the fascination with Kafkas personal neuroses, in the mingling of psychological speculation and literary criticism which frequently led to a false confusion of empirical and literary selves and most importantly in its overall disregard of the playful and humorous dimension in Kafkas texts. Conclusion Kafka’s wanted to share the reality that is happening into our life or others life particularly in our society nowadays. The Metamorphosis was all about Gregor Samsa. This story emphasized the way a man entered the world of despised and how discrimination created hostility. Even his own family tired to suppressed, despised and hurt him not only physically but mentally. The same with our society, the persons who are in the authority sometimes take advantage of everything even to the point that they stepped onto the human rights and privilege of a person. Loving something or someone because you profit from them will not be a good foundation because what if the proceed is gone, are you going to hate him or still love him? Conflict is always present if the environment that we used to stay with is not that aware that justice must be offer to everyone. Hurting people or even killing them without important reason, it’s simply because of selfish desire and hatred won’t make any sense in reality. Instead of doing those things, why don’t we learn to love and forgive them? In the end, we’re going to realize that love is the answer in any changes or metamorphosis that will happen in to our life. Love conquers hatred. Works Cited Peter Kuper Kafka’s The Metamorphosis http://www. randomhouse. com/crown/metamorphosis/ Walker, Jews in Nazi Germany http://www. schoolhistory. co. uk/lessons/germany/jews. html Understanding the Treatment of Jews during World War II http://www. dummies. com/how-to/content/understanding-the-treatment-of-jews-during-world-w. html Edward B. Donnell Jr. , Anti-Semitism in Europe Today http://www. state. gov/p/eur/rls/rm/38113. htm The Cancer of Semitism in Europe http://www. aish. com/societyWork/society/The_Cancer_of_Anti-Semitism_in_Europe. asp

Mutations in KCNQ1 Ion Channel May Cause Jervell and Lange-Nielsen Synd

Mutations in KCNQ1 Ion Channel May Cause Jervell and Lange-Nielsen Syndrome Abstract Jervell and Lange-Nielsen Syndrome is a human disorder that causes deafness and an irregular heartbeat. It is caused by a mutation in a protein that is a potassium ion channel. The mutations lead to a protein that does not serve the purpose it was designed to serve. It is difficult to treat, but there are things that can be done for both the cardiac and auditory aspects of it. Implantation of a device used as a sort of bionic ear can be used as treatment for the deafness characteristic of JLNS. The cardiac portion of JLNS can be treated by either a preventative step or with an implantable device used to stop arrhythmias (irregular beating of the heart) once they have started. Jervell and Lange-Nielsen syndrome is a recessive genetic disorder caused most commonly by mutations in the gene that codes for the KCNQ1 protein. In JLNS, these mutations cause a premature termination of the protein synthesis, leading to a loss of function. It is also known that KCNQ1 can mutate to cause a gain of function (e.g. a quickened heartbeat). Another disorder known as Romano-Ward syndrome involves changing a few of the amino acids within the protein so that the protein retains its basic shape and function, but is a lot less efficient. Without mutations, the KCNQ1 protein is a potassium ion channel, meaning that it transfers potassium ions between a cell and its surroundings. When mutated, KCNQ1 can cause deafness, and long QT syndrome (a disorder in which the heart takes longer to recharge than normal (QT segment is longer than average), often leading to fainting or sudden death.) Jervell and Lange-Nielsen Syndrome affects an estimated 1.6-... ...m.nih.gov/pubmed/18595190?ordinalpos=7&itool=Entrez System2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum [3]Smith, Jarrod A., and Vanoye, Carlos G. and George Jr., Alfred L. and Meiler, Jens and Sanders, Charles R.. "Structural Models for the KCNQ1 Voltage- Gated Potassium Channel." Biochemistry 4614 11 2007 14141-14152. 27 Jul 2008 sample.cgi/bichaw/2007/46/i49/html/bi701597s.html#bi701597sAF2>. [4]"Cochlear Implant." Wikipedia. 27 Jul 2008 . [5]"Long QT Syndrome." Wikipedia. 27 Jul 2008 . [6]"Jervell and Lange-Nielsen Syndrome." Wikipedia. 27 Jul 2008 . [7]"Jervell and Lange-Nielsen Syndrome." WSLH. 27 Jul 2008 .

Saturday Night and Sunday Morning

Director Karel Reisz's Saturday Night and Sunday Morning, the classic story of an angry young man, heralded a new kind of cinema for British audiences. Saturday Night and Sunday Morning is a classic social realist film of the British New Wave. Made in 1960, it was groundbreaking in both its portrayal of the industrial nightmare of working class factory life, and its unrepentant, cocky anti-hero Arthur Seaton. The British New Wave and La Nouvelle Vague Saturday Night and Sunday Morning (1960) was Karel Reisz's first feature film, made in the light of a number of outstanding documentaries from the Free Cinema movement. Interestingly, this film emerged at the same time as Jean-Luc Godard's debut feature A Bout De Souffle (Breathless). Reisz and Godard, the enfant terrible of the French New Wave, shared certain traits. Both were critics turned film-makers whose debut films were the first commercial hits of their respective new waves, and both films were anti-establishment pieces from directors with political agendas. The Angry Young Man Saturday Night and Sunday Morning was a film to which many people could relate. Alan Sillitoe, who adapted his book for the screen, was the creator of one of the original angry young men of cinema history, Arthur Seaton. Arthur is a working class anti-hero whose boredom of factory life is assuaged only by his reckless attitude to life. Trapped in a dead end job, Arthur represents the individual against the system. He makes the most of his leisure time in an attempt to escape the mediocrity of his life. Arthur is blunt and cocky, out for a good time with women, booze and a well cut suit. But he is angry about the restrictions placed on him by his working class life. The cause of this aggression – factory life – united a public who recognized his anger. Cinema attendances reflected the fact that this was one of the first times audiences felt their own lives were represented on screen. Fatally Flawed At the beginning of the film Arthur is having an affair with Brenda, a married woman, who he gets pregnant. He tries to help her when she says she wants an abortion, although ultimately this is unsuccessful. It is a testament to the film-makers that this storyline does not alienate audiences. In fact, for all his gruff, rabble rousing, Arthur remains a likable, if flawed, character. He is seen to get a sort of comeuppance when Brenda's brother in law beats him up at the Nottingham Goose Fair, but audience sympathy is still with Arthur. This is also due in no small part to Albert Finney's amazing portrayal of Arthur as a working class lad coming to bitter terms with the responsibilities of manhood. The Midlands – A Backdrop For Social Realism Setting the film in Nottingham adds a further dimension of imprisonment, through iconography which has since been integrated into British cinema. The imposing chimney stacks and factories serve to increase the feelings of claustrophobia and provincial entrapment. Karel Reisz had already shown in his documentaries Everyday Except Christmas and We Are The Lambeth Boys that ordinary people could provide stories and entertainment, but his directors vision also demonstrates a poeticism of social problems. The views Reisz portrays through his lens have become embedded in British films, and typify a landscape still seen today in any British film within the social realist cannon. Saturday Night and Sunday Morning Saturday Night and Sunday Morning By Alan Sillitoe Adapted by Amanda Whittington [pic] Harrogate Theatre 22nd February – 8th March 2008 Directed by Joyce Branagh Resource Material [pic] Alan Sillitoe's ground breaking picture of 1950's Britain, as seen through the eyes of the unforgettable Arthur Seaton (immortalised on screen by Albert Finney), is now brought raging back to life and bang up-to-date in a fast-moving new stage adaptation.Classic kitchen sink drama blended with high energy action and a toe-tapping 1950's fuelled soundtrack makes this at turns funny and heart-rending tale of the life and loves of the original angry young man a must see for three generations. ContentsPage Brief Synopsis Historical context About the author The adapted text List of Characters Principals Analysis In different media 21st Century references Synopsis Saturday Night and Sunday Morning tells the story of Arthur Seaton, a young Nottingham factory worker, who is having an affair with Brenda , the wife of Jack, an older co-worker.He also has a relationship with Doreen, a woman closer to his own age. When Brenda becomes pregnant with Arthur’s child, he goes to his aunt for advice on aborting the child. Jack discovers the affair. His brother and a fellow soldier give Arthur a serious beating. The play ends on an ambiguous note, with a recovered Arthur and Doreen discussing marriage and the prospect of a new home. Historical context 1958: The European Economic Community (Common Market) starts operation. The birth of Rock and Roll, which resulted in the emergence of clubs. Jerry Lee Lewis’s Great Balls of Fire reaches no 1 in the US charts.Women’s rights were still limited, but this was to change over the coming decade. Marie Stopes, a campaigner for women’s rights, dies, aged 69. The first man-made nuclear fusion was created. The class divide was still very prominent and strong. Labour were in government. Queen Elizabeth II had only recently bee n crowned. The idea of a new age had begun. About the Author Name:Alan Sillitoe Born:4th March 1928, Nottingham. Family:Second son of an illiterate tannery laborer. His father, Christopher Sillitoe, became one of the long-term unemployed during the 1930s Depression.On different occasions he worked as a house painter. Once he was imprisoned for â€Å"running up bills for food that he had no hope of paying. † Sillitoe's mother, Silvina (Burton) worked in a lace factory. â€Å"We lived in a room on Talbot Street whose four walls smelled of leaking gas, stale fat, and layers of mouldering wall-paper,† Sillitoe has recalled. Early life:Left school at 14 Sillitoe’s childhood was shadowed by the financial problems of the family, but he also found early on the joys of literature and started to plan his career as a writer.However, his first semi-fictional tale about his wild cousins was burned by his mother for being too revealing. At the age of 14 he left school and wor ked in a number of jobs in Nottingham factories, including a bicycle factory from 1942 to 1946. He served in the Royal Air Force, where he was a wireless operator. After returning from Malaya, he was discovered to have tuberculosis. Sill toe spent sixteen months in an RAF hospital. During this period he started to write again and read intensively. Pensioned off at 21 on 45 shillings at week, he lived in France and Spain for seven years in an attempt to recover.In 1951 he met an American poet, Ruth Fainlight, who was married, but they decided to go abroad together. From 1952 to 1958 they lived in France, Italy and Spain largely on Sillitoe's air force pension. Encouraged by Robert Graves, whom he met on the island of Mallorca in 1956, Sillitoe began to write his first novel, SATURDAY NIGHT AND SUNDAY MORNING (1958), a story about working-class life in Nottingham. Adapters of the book †¢ Amanda Whittington Previous plays for New Perspectives include: The Boy on the Hill; Last Sto p Louisa’s; and Player’s Angels.Other plays include: Ladies Day (Hull Truck); Satin N Steel (Nottingham Playhouse and Bolton Octagon); Be My Baby (Soho Theatre and subsequently staged by Oldham Coliseum, Hull Truck and Salisbury Playhouse); Born To Run (Third Space); Bollywood Jane (Leicester Haymarket); The Wills’s Girls (Tobacco Factory, Bristol and Radio Four). Publications include: Satin N Steel and Be My Baby (Nick Hern Books); and Twist & Shout, Runaway Girl and Shirley’s Song (SchoolPlay). Amanda has also written for film and television, and was joint winner of the 2001 Dennis Potter Screenwriting Award. David Brett David Brett is an English actor, singer and arranger. David Brett is one of the original members of The Flying Pickets. He arranged a number of the group's songs, including the number one hit Only You. Brett is working as an actor, mainly performing on stage, but he has also participated in a number of TV productions and played Dedalus Diggle in Harry Potter and the Philosopher's Stone[1]. Characters Arthur Seaton: (21) a tall, iron-faced, crop-haired youth Loudmouth: (40) a sailor Brenda: (30) a married mother of two Em’ler: (20’s) Brenda’s friend, a bit touchedWinnie: (25) Brenda’s sister, small and fiery Waiter: too old for the job he’s forced to do Sweeper Girls: (20’s) factory workers Tealady: (40’s) a fixture of the factory Jack: (30) self-contained, fresh-faced, with a perpetual frown Robboe: (40) the foreman, a quiet man with tortured eyes Aunt Ada: (50) the personality of a promiscuous barmaid Mick: (40’s) an Irish drunk Landlady: (50’s) worldly-wise and cynical Courting Couple: (20’s) love-struck Grieving Man: (30’s) confused and sad Doreen: (19) fresh and innocent with a sharp edgeSwaddies: (20’s) army thugs Can be staged with a minimum of six actors, playing: Arthur Brenda/Tealady/Landlady Jack/Loudmouth/Grieving Man/Sw addie Winnie/Aunt Ada/Sweeper Girl/Ratface Doreen/Em’Ler/Sweeper Girl/Courting Girl Waiter/Robboe/Mick/Courting Boy/Swaddie Principal Analysis Arthur: Arthur Seaton, a lathe operator in a bicycle factory in Nottingham, England. The blond, muscular twenty- one-year-old fights to remain independent of society, employers, and marriage. He dates married women—first Brenda, then Winnie—and engages in boisterous drinking bouts.After a beating by Winnie’s soldier husband, he settles for the single Doreen, deciding that he need not reject all that life offers to remain independent. Brenda: Jack’s wife and Arthur’s lover. A young mother of two, she is bored with Jack and finds romance and excitement with Arthur. She is part of the dangerous â€Å"Saturday Night† life of the first half of the novel. After having an abortion, and after Arthur, discovered by Jack, has been beaten, she fades from the action. Doreen Greatton: a factory worker. Nine teen years old and single, she is eager to be married but seeks to curb Arthur’s excesses.She represents marriage and settling down to Arthur in the â€Å"Sunday Morning† half of the novel. She fails to get him past every pub but has won commitment from Arthur at the end. Winnie: nicknamed â€Å"Gyp,† Brenda’s sister. She is livelier and more reckless than her older sister. She, too, has an affair with Arthur. Her husband, Bill, is a soldier stationed in Germany. He returns on leave with a friend and, tipped off to the affair by Jack, beats Arthur. By dating Winnie, Arthur hastens an end to the dangerous life that he is finding to be a strain.Jack: Brenda’s husband and Arthur’s foreman at the factory. He is steady but dull. Rather than confront Arthur, he betrays him to Bill, Winnie’s husband. Aunt Ada: Arthur’s widowed aunt, a large, boisterous, and nurturing mother figure whose house teems with family at Christmas. Following his beating by Winnie’s husband, Arthur becomes withdrawn and cautious. It is in her house, under her vital influence, that Arthur breaks out of his withdrawal and returns to life, but with new attitudes. In different Media Saturday Night and Sunday Morning was first a novel written by Alan Sillitoe in 1958.It was one of the first kinds of Kitchen Sink Drama’s, with other noticeable ones being Angry Young Men and Billy Liar. It was adapted into a film in 1960, starring Albert Finney. The screenplay was adapted by Sillitoe himself. The next adaptation was by David Brett in 1964 as a low budget stage show, with a then unknown Ian McKellen in the role. The next proper adaptation was by Amanda Whittington References and Themes in the 21st Century Adultery Loyalty Revenge Violence Love/Friendship Deceit Rectification of your Mistakes

Dell Supply Chain Analysis - 969 Words

lysDell Supply Chain Analysis Group 11: Mentor: Heidi C. Dreyer Sep-09-2012 Outlines †¢ What’s direct model? †¢ Dell’s position in PC market; – Dell’s competitive strategies; – Implied demand uncertainty analysis; †¢ Dell’s supply chain capabilities; – Facilities; – Inventories; – Transportations; – Information; – Sourcing; – Pricing; – Responsive supply chain; †¢ Strategic fit; †¢ Limitations; †¢ Challenge and proposals for emerging markets; What’s Direct Model? Several supply chain models in push/pull view Make to stock(HC, Lenovo) Build-to order (Direct Model) Push production Pull production Dell’s Position in PC market Service level: high customization, etc Competitive Strategy: Dell chooses the customers who†¦show more content†¦The responsiveness spectrum Somewhat Somewhat efficient responsive Dell: Highly responsive Highly efficient Why it works well 1.Facilities 2.Inventory Service level: high customization, etc 3.Transportation Variety: high variety 4.Information Quality: Reasonable quality 5.Sourcing Price: Reasonable price Lead time: approximately one week 6.Pricing 7.Customer service Strategic Fit Why it works well High implied Uncertainty VS. Responsive SC Strategic Fit--Intercompany Interfunctional Scope †¢ †¢ †¢ Dell SC considered different functions inside the company; Dell SC considered different stages; The intercompany interfunctional scope could obtain the maximize profitability. 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